Senior Clinical Research Associate - Ophthalmology - Small Private CRO - West Coast Location: Remote / Regional Employment Type: Full-Time | Permanent Salary: $130,000–$155,000 + Benefits Travel: Up to 65% | Regional Site Monitoring | West-Coast Therapeutic Area: Ophthalmology Are you an experienced Senior CRA with a strong background in ophthalmology clinical trials looking for an opportunity to take greater ownership of clinical monitoring activities? This is an exciting opportunity to join a well established, specialist Contract Research Organisation, supporting innovative clinical studies focused on advancing treatments within ophthalmology. We are seeking a proactive, detail-oriented Senior Clinical Research Associate located on the west coast who can independently manage investigative sites, build strong relationships with clinical teams, and ensure the successful delivery of high-quality clinical trials. You'll have the opportunity to work on specialist ophthalmology studies, take ownership of site monitoring activities, and provide guidance to junior CRAs within a collaborative clinical operations environment. Key Responsibilities: • Independently manage clinical trial monitoring activities across regional investigative sites. • Conduct site qualification, initiation, interim monitoring, and closeout visits. • Ensure compliance with FDA regulations, ICH-GCP, study protocols, and internal SOPs. • Review source data, case report forms, and regulatory documentation to ensure data quality and integrity. • Monitor patient enrolment, protocol deviations, adverse events, and investigational product accountability. • Build and maintain strong relationships with investigators, study coordinators, sponsors, and clinical teams. • Identify and resolve site-level operational challenges, data discrepancies, and compliance issues. • Provide mentorship and technical guidance to junior CRAs. Candidate Requirements: • Previous ophthalmology clinical trial monitoring experience – essential. • Must be located on the West-Coast • Proven experience as a Senior CRA or experienced CRA with independent site monitoring responsibilities. • Strong background within a CRO, pharmaceutical, or biotechnology environment. • Extensive knowledge of FDA regulations, ICH-GCP, and clinical trial monitoring requirements. • Experience conducting qualification, initiation, interim, and closeout visits. • Strong understanding of clinical data review, regulatory documentation, and investigational product management. • Excellent communication, organisation, and problem-solving skills. • Relevant life sciences or nursing qualification, or equivalent professional experience. • Willingness to travel up to 65% for regional site monitoring activities. What's on Offer? • $130,000–$155,000 base salary. • Remote / home-based working with regional site travel. • Medical, dental, and vision insurance. • Flexible PTO and 401(k) with company match. • Opportunity to work on specialist ophthalmology clinical trials. • Professional development and career progression opportunities.