2025-2030 Focus: To consider science, technical, and policy issues associated with monographs and candidate reference standard materials for herbal ingredients, with emphasis on articles used in the traditional systems in the Pan-American region. Monographs and reference standard materials for articles considered dietary supplements in the U.S. would be considered for adoption into the United States Pharmacopeia (USP) and the USP Dietary Supplements Compendium (DSC). Other monographs and candidates reference standard materials might be considered suitable for entry into the USP Herbal Medicines Compendium (HMC), and for adoption by various pharmacopeias and stakeholders (manufacturers, government laboratories, regulatory agencies). 2025-2030 Key Issues: Specific activities include but are not limited to: • Prioritization of topics for documentary standard development for the Pan Am region • Propose topics for relevant contributions about the science, quality, policy or regulatory aspects of botanical dietary supplements and herbal medicines in the Pan Am region. • Acquisition and review of information to support the development of monographs and candidate reference standard materials for USP and DSC, and possible adoption in the HMC. • Acquisition of analytical samples from plant material from the region and relevant candidates for reference standard materials • Development and collection of laboratory data to support method development and validation, and collaborative testing of candidate reference standard materials • Strengthen relationships with national regulators and international health agencies in topics related to the adoption of USP quality standards for plants used in the practice of Tradicional and Complementary Medicine or in National Health Systems. • Other topics as appropriate and as mutually agreed Required Expertise: The successful candidate would benefit from expertise in the several following areas: Method development/method optimization/method validation; reference standard evaluation; pharmacognosy; chemometrics; chromatography [Liquid (H/UPLC), Gas, Planar (HPTLC)]; analytical spectroscopy [IR/Raman, NMR/qNMR, flame/plasma, Light Scattering, UV-Vis, NIR, XRF/XRD]; titrimetry: [potentiometric including ISE, Karl Fischer]; mass spectrometry; Quality by Design; multivariate/chemometric analysis; wet chemistry; DNA analysis; plant taxonomy; microbiologic analysis; detection of adulteration; Complementary and Integrative medicine; regulatory science.