The Position Product Engineering Manager - Commercial Pharma US Targeting, Recommendation, Optimization and Measurement Roche Digital Technology (RDT) is where innovation meets purpose. As a global team at the heart of Roche, we are a community of business-minded technologists committed to help shape tomorrow’s digital future of healthcare. Our mission is to power Roche through cutting-edge digital technologies, harnessing the potential of artificial intelligence, data, and scalable tech innovations. Driven by purpose and passion, we’re building a future where digital is a core strength across all of Roche, enabling smarter ways of working, unlocking human potential, and driving breakthroughs that truly matter for millions of patients around the world. The Opportunity As a Product Engineering Manager of Commercial Pharma US Targeting, Recommendation, Optimization and Measurement, you will sit at the intersection of cutting-edge technology and life-changing medicine. You will lead a team responsible for architecting scalable digital solutions that transform commercial intent into business impact while fostering a high-performing, sustainable engineering culture. This role partners closely with the Genentech business product owners that support key business commercial functions of measurement (e.g., segmenting HCPs, dynamic lists, geospatial analysis etc.), recommendation (e.g., Next Best Action), optimization (e.g., measurable ROI, “what-if” simulations etc.) and Measurement (e.g., Attribution modeling, operational health etc.). Actual title will be Team Lead Engineering Commercial Pharma US Targeting, Recommendation, Optimization and Measurement. Key Responsibilities • Define the architectural roadmap and select digital technologies for enterprise-level customer engagement. Ensure engineering output meets ROI and adoption targets. • Partner with Business Product Owners to translate roadmaps into high-fidelity technical plans for segmenting, "what-if" simulations, and attribution modeling. • Mentor team members on long-term career paths. Build a future-focused talent portfolio by balancing technical skills with healthy team dynamics. • Oversee end-to-end delivery performance across the product group. Resolve systemic, cross-functional roadblocks and drive process re-engineering to boost efficiency. • Manage the team budget (headcount, vendors, operations) and strategically allocate resources across the portfolio to maximize impact. Who You Are • Bachelor’s degree in Engineering, Science, or Business (Master’s preferred). • 5+ years in people leadership or program management; 2+ years in Pharma/Biotech or regulated healthcare. • Proven track record in deploying BI solutions (predictive/prescriptive), modern visualization tools, and ML/AI toolsets. • A servant leader (VACC) with an enterprise mindset, capable of navigating ambiguity and breaking down organizational silos. • Strong business acumen, lean/agile mindset, and the ability to empower autonomous teams while maintaining accountability. The expected salary range for this position based on the primary location of South San Francisco, CA is $149,700 - $278,100. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are not available for this job posting. #RDT2026 Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.