The role: BigHat Biosciences is looking for a hands-on, bench-driven scientist to perform IND-enabling developability assessments on late stage drug candidates from our Milliner Platform for AI-designed therapeutics. This is a lab-based 12-month contract role, with the possibility but no guarantee of conversion to full-time position. You'll spend the majority of your time at the bench executing complex stability studies. Key Responsibilities • Lead, design, and execute in-use dose solution studies to assess drug compatibility with administration materials. • Develop highly sensitive protein characterization methods (qSEC, RP-HPLC, CEX, particle counting, etc) for assessing drug quality and recovery. • Support late-stage characterization, including formulation screening, stress testing, and peptide mapping, to rank and advance lead candidates. • Drive developability assessments (purity, stability, tolerability, biophysical properties) across programs, with strong attention to data interpretation and organization. • Communicate with and manage external CROs for testing and analytics. • Interpret and communicate scientific findings, propose next steps, and broadcast clearly across the organization. • Proactively identify and scope state-of-the-art analytical tools and developability technologies. Skills Knowledge and Expertise • PhD in Biochemistry or relevant discipline with 5+ year(s) of industry experience; exceptional non-PhD candidates with deep bench experience will be considered. • Experience developing and optimizing sensitive analytical chromatography-based methods is a must. • Strong background in biophysical and analytical characterization of antibodies and antibody fragments: SEC, HIC, CE-SDS, DLS, DSF, ELISA, LC-MS. • Track record of translating complex data into clear results and recommended actions. • Enthusiastic about learning and onboarding new technologies to expand capabilities and improve work quality, timelines, throughput or cost.