Exonic Biosciences · Dogpatch, San Francisco $120K–$180K a year + equity Exonic is building AI systems for programmable biology. We train multimodal foundation models on large-scale biological datasets to design synthetic non-coding DNA. We experimentally validate our AI-designed systems in mammalian cells, with current applications in cell-type targeting and viral vector biomanufacturing. Our core focus is synthetic regulatory DNA. We have already generated strong in vitro cell-type targeting results and are expanding our internal experimental platform in San Francisco. We are looking for an ambitious experimental scientist to take ownership of Exonic’s wet-lab work and help push the platform into new directions. You would work directly with the founder as one of the first people in the company. What you’ll work on • Own and execute experimental validation of AI-designed regulatory DNA • Design and run cell-based assays for synthetic enhancer and expression systems • Help advance programs in cell-type targeting and AAV manufacturing • Help shape Exonic’s experimental roadmap as the company grows Relevant experience • Molecular biology, synthetic biology, regulatory genomics, or gene therapy • Mammalian cell culture and cell-based assays • Cloning, plasmid design, transfection, qPCR/ddPCR, sequencing, flow, luciferase, or related workflows • AAV biology/manufacturing experience is a major plus We care most about ownership, execution speed, and comfort with ambiguity. This is an early-stage role with autonomy, and the opportunity to build the biological engine of an AI-native synthetic DNA company. Location: San Francisco / MBC BioLabs