Overview We are seeking a Senior Manager, FP&A to join our Boston-based Finance team. Reporting to the Director, FP&A, this individual will support and own planning, forecasting, and analytics across a significant portion of the Company's operating expense base, partnering directly with department leaders to translate strategic priorities into credible financial plans. This is a broad, high-visibility role with exposure to both our scientific organization and our corporate functions. You will be a core contributor to the annual planning cycle, quarterly reforecasts, monthly close, cash and runway analysis, and Board-level reporting. The scope is intentionally wide — we are looking for someone who wants to understand how the whole company works, not just one slice of it. Responsibilities Operating plan and forecasting: Own the annual operating plan, quarterly reforecasts and long-range plan for assigned areas. Driver-based modeling: Build and maintain driver-based models for headcount, personnel costs, external spend, consumables, capital and allocations. Variance analysis and reporting: Prepare monthly and quarterly reporting packages with budget-versus-actual variance analysis. Include forward-looking commentary on the full-year outlook. Cash and runway modeling: Contribute to cash forecasting, burn analysis and runway management. Support financing planning, Board materials, budget presentations and external operating expense guidance. Contract and investment modeling: Build financial models and decision support for CRO/CDMO and vendor contracts, collaborations, capital equipment, software and facilities. Evaluate resource allocation trade-offs across programs, platforms and infrastructure. Headcount and compensation modeling: Model headcount plans, compensation cycles, recruiting plans and payroll/benefits forecasts with People Experience & Operations. Month-end close and expense accounting: Work with Accounting on accruals, reclasses and spend validation. Check that expense classification follows policy and external reporting requirements. Systems, controls and process: Improve FP&A processes, reporting templates and self-service reporting in NetSuite and planning tools. Support internal controls, SOX-readiness and audit requests on budgeting and forecasting. Qualifications Education: Bachelor's degree in Finance, Accounting, Economics or a related quantitative field. Experience: 7–10+ years of progressive FP&A, corporate finance or accounting experience. Budget and forecast ownership: Demonstrated ownership of multiple full budget and forecast cycles for meaningful cost centers, including direct work with senior non-finance leaders. Modeling: Advanced Excel and financial modeling skills, able to build a clean, auditable, flexible model from a blank sheet. Accounting: Strong command of accrual accounting and the month-end close process. Preferred biotech and systems background: Biotech, pharma or life sciences experience, ideally at a clinical-stage company, with exposure to R&D cost centers. Also hands-on NetSuite and an EPM/planning tool (e.g., Adaptive), plus familiarity with public company reporting (10-Q/10-K, SOX, Board reporting).