• Perform line clearance before starting compression activities. • Verify cleanliness and status labels of compression machine, tooling, and accessories. • Ensure availability of approved Batch Manufacturing Record (BMR). • Verify granules/blend details and status labels before use. • Install and set up punches, dies, and turret as per product requirements. • Operate tablet compression machine according to approved parameters. • Adjust machine settings for tablet weight, hardness, thickness, and compression force. • Monitor critical process parameters during compression. • Perform and record in-process checks at specified intervals. • Ensure tablet appearance, weight variation, thickness, friability, and hardness are within specifications. • Collect samples for in-process testing as per BMR. • Minimize tablet defects such as capping, lamination, sticking, picking, and chipping. • Reconcile product quantities during and after batch completion. • Complete all BMR entries accurately and in real time. • Maintain equipment usage and logbook records. • Follow Good Documentation Practices (GDP) and Data Integrity requirements. • Prevent mix-up and cross-contamination during operations. • Clean compression machine, punches, dies, and area after batch completion. • Report deviations, machine breakdowns, and abnormalities immediately. • Follow cGMP, safety requirements, and wear appropriate PPE. • Maintain housekeeping and cleanliness in the compression area. Ensure product quality, safety, and regulatory compliance throughout the compression process. ITI/ Diploma