Senior Mechanical Engineer Compensation: $100k – $150k salary + 0.1%– 0.25% equity + benefits Full benefits, including health coverage, PTO & parental leave About BiomeSense BiomeSense is a life sciences startup applying gut microbiome technologies (GutLab, MetaBiome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by LabCorp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners. Key Responsibilities You will own key technical workstreams responsible for the success of our next-generation GutLab hardware, while providing hands-on support. • Mechanical Design of Novel Hardware: Devise elegant solutions to complex mechanical design problems, balancing performance, risk, and timelines • Systems Integration: Integrate mechanical, electrical, and fluidic systems into robust products; resolve system-level tradeoffs • Hardware Build & Test: Perform detailed electrical, mechanical, and fluidic assembly of prototypes and sub-assemblies; lead hands-on validation of new designs • Troubleshooting & Repair: Diagnose and repair complex hardware, software, and firmware issues in lab and field; identify root causes and drive fixes • Testing & Automation: Design and improve test setups, fixtures, and automation to optimize assembly and validate hardware; maintain a clean, organized, inventoried hardware lab • Documentation & Quality: Create clear SOPs, manuals, test records, and design documentation for repeatable production; flag risks and assembly feedback early Qualifications • Bachelor’s Degree in Engineering or related field and 5+ years in hardware development • Experience independently designing complex, novel hardware and test fixtures using CAD • Proven ability and willingness to perform precise, hands-on assembly and testing of complex electromechanical hardware • Experience with prototyping techniques (e.g., 3D printing, light machining) • Proven ability to perform detailed wiring, harnessing, and soldering • Highly organized, proactive, and independent; owns ambiguous work through resolution and collaborates across disciplines • Experience with instrument control software and scripting; able to interpret test results and translate findings into design improvements Preferred Qualifications: • Experience taking a new product from prototype to production • Expertise in Design for Assembly (DFA) and Design for Manufacturing