Associate Scientist I – Histotechnician Hourly Rate: $33 - $36/hr with medical benefits available at a cost Contract Length: Initial contract through 7/25/27 Location: Onsite in Irvine, CA Work Schedule: Monday – Friday 9 am to 5 pm Position Summary We are seeking a detail-oriented and experienced histotechnician for an 8-month contract position supporting routine histology and immunohistochemistry (IHC) operations within the histology laboratory for Skincare R&D and Clinical Development. This is a hands-on, lab-based role responsible for the processing, sectioning, and staining of formalin-fixed paraffin-embedded (FFPE) tissues, as well as performing special stains, IHC assays, and associated imaging/documentation. The ideal candidate is comfortable working independently in a fast-paced environment, maintains rigorous attention to quality and consistency, and has solid foundational histology bench skills. Key Responsibilities • Perform routine processing of FFPE tissue specimens, including trimming, embedding, and block preparation • Section FFPE tissue blocks using a microtome to produce high-quality, consistent slides for downstream analysis • Perform routine histology staining (e.g., H&E) and special stains (e.g., Fontana-Masson, Resorcin Fuchsin, Herovici, etc.) per established SOPs • Perform manual and/or automated immunohistochemistry (IHC) staining, including antigen retrieval, antibody optimization support, and chromogenic/fluorescent detection • Operate and maintain histology laboratory equipment (microtomes, tissue processors, embedding stations, autostainers, coverslippers) • Perform slide imaging/scanning and organize digital image files for study team review • Maintain accurate, detailed records of samples, staining runs, and quality control checks in line with lab documentation practices • Troubleshoot staining and tissue quality issues, escalating as appropriate • Ensure proper labeling, tracking, and chain-of-custody for tissue specimens and slides • Maintain lab supplies, reagents, and equipment calibration/maintenance logs • Adhere to all laboratory safety protocols, including handling of chemicals (formalin, xylene, etc.) and biohazardous materials • Support general lab organization, inventory management, and cleanliness standards • Collaborate with scientists and lab management within Skincare R&D and Clinical Development to meet study timelines and quality expectations Required Qualifications • Associate's or Bachelor's degree in a relevant scientific field (e.g., Biology, Medical Laboratory Science, Histotechnology) • Minimum of 1–3 years of hands-on experience in a histology laboratory, including FFPE tissue processing, microtome sectioning, and routine/special staining • Strong attention to detail and consistency in a high-throughput lab environment • Ability to work independently with minimal supervision while following established SOPs • Good documentation and record-keeping habits • Ability to safely handle laboratory chemicals and biological specimens Preferred Qualifications • HT or HTL certification (ASCP) or eligibility • Demonstrated experience performing IHC staining (manual and/or automated platforms) • Familiarity with slide imaging/digital scanning workflows • Experience with automated IHC/special stain platforms (e.g., Leica Bond, Ventana/Roche Discovery, Dako Autostainer) • Experience with whole-slide imaging/scanning systems • Prior experience in a pharmaceutical, biotech, or CRO research lab setting (as opposed to clinical diagnostics) • Familiarity with GLP or GxP laboratory documentation practices • Experience in skincare/dermatology-focused research or clinical development studies is a plus People are our business worldwide Orion Group was founded in 1987 and is now one of the largest, independent, international recruitment companies. We have a network of 200 employees working from 24 offices, delivering a range of services – Talent Acquisition, Recruitment Outsourcing Services, Retained Search, Global Workforce Solutions, Completions & Commissioning and Materials Management – across 68 countries. As a global leader in workforce solutions, we recruit personnel across the Engineering & Technical, Office & Commercial, Scientific and Skilled Trades disciplines, for sectors including Oil & Gas, Life Science, Power & Utilities, Constructions & Infrastructure, Manufacturing and Renewables.