Registered Nurse (RN) jobs in Charleston, South Carolina

82 open Registered Nurse (RN) jobs in Charleston, South Carolina (2 posted in the last 7 days), collected from employers’ own career pages and checked twice a day. Every listing links to the company’s site to apply.

Latest openings

• Registered Nurse -Implant Coordinator

  Veterans Health Administration · Charleston
  Posted 2026-10-20
• Registered Nurse (RN) — Cardiac Intermediate Care — Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-21
• Registered Nurse (RN) Weekend Only – Nephrology – Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-21
• Registered Nurse (RN) — Nephrology — Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-21
• Registered Nurse (RN) - Rehab Med Surg - Roper Hospital - 3 West - Weekend Only

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-21
• Registered Nurse -Lung Cancer Screening Clinical Coordinator

  Veterans Health Administration · Charleston
  Posted 2026-10-21
• Registered Nurse (RN) - Med Surg - Bon Secours St. Francis Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-21
• Registered Nurse (RN) - Med Surg Urology - Bon Secours St. Francis Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-21
• Registered Nurse (RN) - Medical Intermediate Care/Hospitalist - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-21
• Registered Nurse (RN) - Cardiac Intermediate Care - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-20
• Registered Nurse (RN) - Operating Room (OR) - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-19
• Registered Nurse (RN) or Invasive Cardiovascular Technologist (RCIS) - Cath Lab - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-16
• Registered Nurse Wound Care

  iDeal Hire · Charleston
  Posted 2026-10-14
• Observation Registered Nurse

  iDeal Hire · Charleston
  Posted 2026-10-05
• Pre Op PACU RN

  USPI · Charleston
  Posted 2026-10-09
• Registered Nurse (RN) Weekend Only Plan - Cardiac Intermediate Care - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-15
• Registered Nurse (RN) - NSG Bone Marrow Transplant - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-14
• Registered Nurse (RN) – Nephrology – Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-14
• Registered Nurse (RN) - Emergency Department (ED) - Roper Hospital - PRN

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-14
• Registered Nurse (RN) - Acute Med Surg - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-14
• Registered Nurse (RN) — Labor And Delivery - Bon Secours St. Francis Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-12
• Registered Nurse (RN) - Oncology - West Ashley Cancer Center

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-14
• Registered Nurse (RN) - Labor And Delivery - Bon Secours St. Francis Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-14
• Registered Nurse - CVOR

  Prolink · Charleston
  Posted 2026-09-02
• Remote Hospice Triage RN FT Monday-Friday 8:30a-5p (No Wknds)

  IntellaTriage · Charleston · Remote
  Posted 2026-10-09
• Registered Nurse (RN) - Emergency Department (ED) - Roper Hospital - Weekend Only

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-06
• Registered Nurse (RN) - Emergency Department (ED) - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-06
• Registered Nurse (RN) Weekend Only Plan — Cardiac Intermediate Care — Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-08
• Registered Nurse (RN) - Physician Practice - Charleston OBGYN

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-08
• Registered Nurse (RN) - PreOp and Post-Anesthesia Care Unit (PACU) - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-10-09
• PRN Registered Nurse Case Manager

  UNIFI Healthcare · Charleston · Hybrid
  Posted 2026-08-04
• PRN RN Case Manager

  UNIFI Healthcare · Charleston · Remote
  Posted 2026-09-28
• Need Registered Nurse (with ACLS and BLS Certifications)

  US IT Solutions Inc. · Charleston
  Posted 2017-08-10
• Registered Nurse RN

  Riverside Health and Rehabilitation · Charleston
  Posted 2024-10-06
• Registered Nurse Assessment Coordinator (MDS) (RNAC)

  Riverside Health and Rehabilitation · Charleston
  Posted 2024-10-06
• Wound Care Registered Nurse RN

  Riverside Health and Rehabilitation · Charleston
  Posted 2024-10-06
• Need Registered Nurse (with ACLS /BLS Certifications)

  IT Professionals · Charleston
  Posted 2017-08-10
• ICU, ER, OR, Transplant, Onco, NICU, M/S (RN) - CHARLESTON, South Carolina

  Launch Healthcare · Charleston
  Posted 2025-07-23
• Chemotherapy/Infusion Registered Nurse

  Artemisarc · Charleston
  Posted 2026-04-17
• Medical Surgical Registered Nurse (RN)

  Aptive Resources · Charleston
  Posted 2026-08-07
• Chemotherapy/Infusion Registered Nurse

  Aptive Resources · Charleston
  Posted 2026-04-17
• Registered Nurse

  Greenberg & Larraby, Inc. (GLI) · Charleston
  Posted 2026-01-06
• ARCA School Nurse

  American Classical Education · Charleston
  Posted 2025-02-12
• Registered Nurse (RN) Weekend Only – Buxton Surgical Pavilion – Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-05-12
• Registered Nurse (RN) - Cardiothoracic And Vascular Intermediate Care - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-05-12
• Registered Nurse (RN) - Cardiothoracic And Vascular Intermediate Care - Roper Hospital - Weekend Only

  Roper St. Francis Healthcare · Charleston
  Posted 2026-05-12
• Registered Nurse (RN) — Cardiac Intermediate Care — Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-06-03
• Registered Nurse (RN) — Oncology — Roper Hospital — Weekend Only

  Roper St. Francis Healthcare · Charleston
  Posted 2026-06-19
• Registered Nurse (RN) - Acute Med Surg - Roper Hospital

  Roper St. Francis Healthcare · Charleston
  Posted 2026-06-30
• Registered Nurse (RN) – Med Surg – Roper Hospital – 6 South

  Roper St. Francis Healthcare · Charleston
  Posted 2026-06-30

Also see

• Entry-level Registered Nurse (RN) jobs in Charleston, South Carolina 10

Registered Nurse (RN) jobs in other cities

• Atlanta, Georgia 640
• Houston, Texas 548
• Los Angeles, California 382
• Miami, Florida 377
• Dallas, Texas 367
• Jackson, Mississippi 364
• Memphis, Tennessee 346
• Charlotte, North Carolina 342
• San Antonio, Texas 334
• Huntsville, Alabama 320
• Cincinnati, Ohio 319
• Chicago, Illinois 316
• Grand Rapids, Michigan 280
• New Orleans, Louisiana 274
• Nd, North Dakota 257
• Nashville, Tennessee 248
• Charlottesville, Virginia 245
• Greenville, South Carolina 243
• Jacksonville, Florida 234
• Milwaukee, Wisconsin 233
• Indianapolis, Indiana 232
• Augusta, Georgia 222
• Madison, Wisconsin 212
• Louisville, Kentucky 205
• Omaha, Nebraska 204

Other roles in Charleston, South Carolina

• Server / Bartender / Host 70
• Cook / Chef 65
• Store / Shift Manager 59
• Sales Representative 55
• Customer Service Representative 50
• Technician (general) 49
• Teacher / Tutor 48
• Delivery / Truck Driver 47
• Restaurant Crew / Team Member 46
• Program / Project Manager 45
• Maintenance Technician 40
• Automotive / Service Technician 39
• Patient Care / Caregiver 38
• Retail Sales Associate 36
• Hotel / Housekeeping 36
• Intern / Trainee 34
• Supervisor / Team Lead (other) 30
• Construction / Carpenter / Labor 29
• Physician / Doctor 28
• Retail Associate (other) 25
• Medical Assistant 25
• HVAC / Plumbing 25
• Operations Manager 23
• Banker / Relationship Manager 22

Questions

How many Registered Nurse (RN) jobs are open in Charleston, South Carolina right now?

82 listings are open on OpeningsFirst today, all from employers’ own career pages. 2 more were posted in the last 5 days and went to subscribers first.

Which companies are hiring for Registered Nurse (RN) roles in Charleston, South Carolina?

Recent openings here come from Veterans Health Administration, Roper St. Francis Healthcare, iDeal Hire, USPI, Prolink, IntellaTriage, UNIFI Healthcare, US IT Solutions Inc..

How do I hear about new Registered Nurse (RN) jobs in Charleston, South Carolina first?

Subscribers get new matching jobs by email at 8 am and 6 pm, 5 days before they open on these pages. It costs ₹299 a month.

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