Machine Learning / AI Engineer jobs in South San Francisco, California

21 open Machine Learning / AI Engineer jobs in South San Francisco, California, collected from employers’ own career pages and checked twice a day. Every listing links to the company’s site to apply.

Latest openings

• Advanced Data Science Associate Consultant - Generative AI and Machine Learning

  ZS · South San Francisco
  Posted 2026-01-18
• Senior Director, AI Engineering

  ZS · South San Francisco
  Posted 2026-07-30
• Director/Senior Director, AI/ML for Drug Discovery

  Septerna · South San Francisco
  Posted 2026-10-15
• Machine Learning Engineer

  Andromeda Surgical · South San Francisco
  Posted 2026-09-04
• Computer Vision/Deep Learning Scientist

  iSono Health · South San Francisco
  Posted 2019-06-04
• Applied AI Engineer (LLMs, Agents, and Healthcare AI)

  Human Longevity, Inc. · South San Francisco
  Posted 2026-07-10
• Senior/Principal Machine Learning Scientist, Perturbation Biology, AI Biology & Translation (AIBT)

  Genentech · South San Francisco
  Posted 2026-09-18
• Senior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT)

  Genentech · South San Francisco
  Posted 2026-09-19
• Software Development Engineer/Senior Software Development Engineer, Agentic Systems, AI for Drug Discovery

  Genentech · South San Francisco
  Posted 2026-09-07
• Senior Scientist, Antibody Developability/Biophysics & Portfolio Support, AI for Drug Discovery (AIDD)

  Genentech · South San Francisco
  Posted 2026-08-14
• Machine Learning Engineer, Infra, AI for Drug Discovery

  Genentech · South San Francisco
  Posted 2026-08-15
• Senior Machine Learning Engineer, Agentic Science/Generative Models, AI for Biology & Translation (AIBT)

  Genentech · South San Francisco
  Posted 2026-09-10
• Research Scientist, Machine Learning

  onepot · South San Francisco
  Posted 2026-08-07
• Senior Manager, Imaging Machine Learning

  insitro · South San Francisco · Hybrid
  Posted 2026-06-11
• Senior Machine Learning Scientist, Imaging

  insitro · South San Francisco · Hybrid
  Posted 2026-02-17
• ML Infrastructure Engineer

  Zipline · South San Francisco
  Posted 2026-09-09
• Machine Learning Engineer Intern

  Neuralink · South San Francisco
  Posted 2025-05-30
• BioMedical AI Research Engineer

  Xaira Therapeutics · South San Francisco · Hybrid
  Posted 2026-03-31
• AI Scientist - Biomedical Multimodal Modeling

  Xaira Therapeutics · South San Francisco
  Posted 2026-05-04
• AI Scientist, BioMedical AI

  Xaira Therapeutics · South San Francisco
  Posted 2026-01-26
• AI in Residence

  Xaira Therapeutics · South San Francisco
  Posted 2026-03-25

Machine Learning / AI Engineer jobs in other cities

• New York, New York 646
• San Francisco, California 586
• Seattle, Washington 260
• Mountain View, California 198
• Sunnyvale, California 179
• Palo Alto, California 159
• Santa Clara, California 136
• San Jose, California 120
• Austin, Texas 119
• Boston, Massachusetts 106
• San Francisco, New York 93
• Atlanta, Georgia 73
• McLean, Virginia 71
• San Diego, California 70
• Redmond, Washington 70
• Chicago, Illinois 69
• Arlington, Virginia 60
• Bellevue, Washington 59
• Jersey City, New Jersey 57
• San Mateo, California 55
• Dallas, Texas 51
• Plano, Texas 44
• San Francisco, Washington 38
• Irvine, California 37
• Chantilly, Virginia 37

Other roles in South San Francisco, California

• Research Scientist 95
• Intern / Trainee 70
• Executive / Director 52
• Mechanical Engineer 31
• Software Engineer 27
• Electrical / Electronics Engineer 24
• Program / Project Manager 22
• Supervisor / Team Lead (other) 17
• Product Manager 15
• Lab / Clinical Research 14
• Delivery / Truck Driver 14
• Technician (general) 13
• Supply Chain / Procurement 12
• Security Officer / Guard 12
• Operations Manager 12
• QA / Test Engineer 11
• Engineering Manager 10
• Engineer (other) 10
• Account Manager / Key Account 10

Questions

How many Machine Learning / AI Engineer jobs are open in South San Francisco, California right now?

21 listings are open on OpeningsFirst today, all from employers’ own career pages. 0 more were posted in the last 5 days and went to subscribers first.

Which companies are hiring for Machine Learning / AI Engineer roles in South San Francisco, California?

Recent openings here come from ZS, Septerna, Andromeda Surgical, iSono Health, Human Longevity, Inc., Genentech, onepot, insitro.

How do I hear about new Machine Learning / AI Engineer jobs in South San Francisco, California first?

Subscribers get new matching jobs by email at 8 am and 6 pm, 5 days before they open on these pages. It costs $9 a month.

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