How many jobs paying $100k+ are open in South San Francisco, California right now?

49 listings are open on OpeningsFirst today, all from employers’ own career pages. 0 newer ones went to members by email, within hours of being posted.

Which companies are hiring in South San Francisco, California?

Recent openings here come from Genentech, Goodwin Recruiting, MSD (Merck & Co., Inc.), Zipline, insitro, Exos, Nkarta, Inc., Hearst Communications.

Which site alerts me to new jobs paying $100k+ in South San Francisco, California?

OpeningsFirst emails new jobs paying $100k+ in South San Francisco, California the day employers post them on their own career pages, checking 108,296 career sites. Many never reach LinkedIn. Listings older than 5 days are free to browse here; 49 are open on this page now.

How do I hear about new jobs paying $100k+ in South San Francisco, California first?

Members get new matching jobs by email at 8 am and 6 pm, within hours of being posted, so they apply among the first. It costs $9 a month.

Jobs paying $100k+ in South San Francisco, California

14 new this week · 48 open · from company career pages

Get new jobs paying $100k+ in South San Francisco, California by email, the day they’re posted ↓

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1–48 of 48

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Role	Company	Location	Pay a year	Experience	Posted
Senior Software Engineer - Lab Automation NewSenior	Genentech	South San Francisco, California On-site	$204k	5+ yrs	7d ago
Senior Software Engineer - Lab Automation at Genentech Software engineering for lab automation and autonomous lab workcells Where South San Francisco, California (On-site) Level Senior, 5+ yrs Pay $204k a year, stated by the employer (middle of the range) Posted Posted 7 days ago PythonC# View the job and apply
VP, Commercial Lending NewVP / C-level	Goodwin Recruiting	South San Francisco, California	$100k	5+ yrs	7d ago
VP, Commercial Lending at Goodwin Recruiting Commercial lending Where South San Francisco, California Level VP / C-level, 5+ yrs Pay $100k a year, stated by the employer (middle of the range) Posted Posted 7 days ago NetworkingUnderwriting View the job and apply
Principal Scientist, Translational Immunology & Antibody Discovery InnovationLead / Manager	MSD (Merck & Co., Inc.)	South San Francisco, California	$227k	–	8d ago
Principal Scientist, Translational Immunology & Antibody Discovery Innovation at MSD (Merck & Co., Inc.) Translational immunology and antibody discovery research Where South San Francisco, California Level Lead / Manager Pay $227k a year, stated by the employer (middle of the range) Posted Posted 8 days ago View the job and apply
Director of CybersecurityDirector	Zipline	South San Francisco, California	$325k	–	8d ago
Director of Cybersecurity at Zipline Cybersecurity leadership Where South San Francisco, California Level Director Pay $325k a year, stated by the employer (middle of the range) Posted Posted 8 days ago LogisticsEmbeddedCybersecurityLegal View the job and apply
Lead/ Senior Machine Learning Scientist, Integrative PhenotypingLead / Manager	insitro	South San Francisco, California Hybrid	$204k	5+ yrs	9d ago
Lead/ Senior Machine Learning Scientist, Integrative Phenotyping at insitro Machine learning science for phenotyping Where South San Francisco, California (Hybrid) Level Lead / Manager, 5+ yrs Pay $204k a year, stated by the employer (middle of the range) Posted Posted 9 days ago Machine learningClinical View the job and apply
General ManagerLead / Manager	Exos	South San Francisco, California	$100k	7+ yrs	9d ago
General Manager at Exos General management Where South San Francisco, California Level Lead / Manager, 7+ yrs Pay $100k a year, stated by the employer (middle of the range) Posted Posted 9 days ago SwiftInsurance View the job and apply
Senior Director/Executive Director, BiostatisticsDirector	Nkarta, Inc.	South San Francisco, California	$330k	–	10d ago
Senior Director/Executive Director, Biostatistics at Nkarta, Inc. Biostatistics leadership Where South San Francisco, California Level Director Pay $330k a year, stated by the employer (middle of the range) Posted Posted 10 days ago ClinicalEmbedded View the job and apply
Principal Strategic Partner ManagerLead / Manager	Hearst Communications	South San Francisco, California Hybrid	$180k	10+ yrs	12d ago
Principal Strategic Partner Manager at Hearst Communications Strategic partner account management and renewal for a healthcare data partner Where South San Francisco, California (Hybrid) Level Lead / Manager, 10+ yrs Pay $180k a year, stated by the employer (middle of the range) Posted Posted 12 days ago PharmacyClinicalLegal View the job and apply
Software Engineer, Fraud System Interventions	Stripe	South San Francisco, California	$253k	–	2w ago
Software Engineer, Fraud System Interventions at Stripe Fraud system interventions software engineering Where South San Francisco, California Pay $253k a year, stated by the employer (middle of the range) Posted Posted 14 days ago PythonJavaSQLData scienceLegal View the job and apply
Sr. Sales Account Manager - BiosciencesLead / Manager	Thermo Fisher	South San Francisco, California	$122k	8+ yrs	2w ago
Sr. Sales Account Manager - Biosciences at Thermo Fisher Key account sales for biosciences Where South San Francisco, California Level Lead / Manager, 8+ yrs Pay $122k a year, stated by the employer (middle of the range) Posted Posted 14 days ago Salesforce View the job and apply
Senior Director, Field Excellence Analytics NewDirector	Genentech	South San Francisco, California Hybrid	$215k	12+ yrs	7d ago
Senior Director, Field Excellence Analytics at Genentech Senior director leading field force effectiveness analytics for pharma sales teams Where South San Francisco, California (Hybrid) Level Director, 12+ yrs Pay $215k a year, stated by the employer (middle of the range) Posted Posted 7 days ago Data scienceEmbeddedCompliance View the job and apply
Senior Machine Learning Scientist - Lab Automation NewSenior	Genentech	South San Francisco, California On-site	$240k	3+ yrs	7d ago
Senior Machine Learning Scientist - Lab Automation at Genentech Build computer vision and multimodal ML systems for autonomous drug discovery labs Where South San Francisco, California (On-site) Level Senior, 3+ yrs Pay $240k a year, stated by the employer (middle of the range) Posted Posted 7 days ago Machine learningComputer visionAgenticPyTorchMLOpsPython View the job and apply
Scientist, Laboratory Animal Resources (On-site)	MSD (Merck & Co., Inc.)	South San Francisco, California On-site	$139k	–	8d ago
Scientist, Laboratory Animal Resources (On-site) at MSD (Merck & Co., Inc.) Laboratory animal resources and care Where South San Francisco, California (On-site) Pay $139k a year, stated by the employer (middle of the range) Posted Posted 8 days ago Clinical View the job and apply
Marketing Manager, Ophthalmology MarketingLead / Manager	Genentech	South San Francisco, California	$184k	–	8d ago
Marketing Manager, Ophthalmology Marketing at Genentech Ophthalmology marketing manager planning omnichannel campaigns and launches for eye-care products Where South San Francisco, California Level Lead / Manager Pay $184k a year, stated by the employer (middle of the range) Posted Posted 8 days ago MarketingCompliance View the job and apply
Manager, Product Public RelationsLead / Manager	Genentech	South San Francisco, California	$152k	6+ yrs	8d ago
Manager, Product Public Relations at Genentech Pharmaceutical product public relations and communications management Where South San Francisco, California Level Lead / Manager, 6+ yrs Pay $152k a year, stated by the employer (middle of the range) Posted Posted 8 days ago MarketingClinicalCompliance View the job and apply
Legal Counsel, Therapeutic Area Products	Genentech	South San Francisco, California On-site	$260k	5+ yrs	8d ago
Legal Counsel, Therapeutic Area Products at Genentech In-house pharma legal counsel advising on commercialization and product lifecycle Where South San Francisco, California (On-site) Level 5+ yrs Pay $260k a year, stated by the employer (middle of the range) Posted Posted 8 days ago MarketingComplianceLegal View the job and apply
Senior Software Engineer - Lab AutomationSenior	Genentech	South San Francisco, California	$204k	5+ yrs	8d ago
Senior Software Engineer - Lab Automation at Genentech Full-stack software engineering for lab automation and scientific workflow tools Where South San Francisco, California Level Senior, 5+ yrs Pay $204k a year, stated by the employer (middle of the range) Posted Posted 8 days ago ReactTypeScriptPythonSQLAWS View the job and apply
Contract Strategy Implementation DirectorDirector, contract	Genentech	South San Francisco, California	$209k	12+ yrs	8d ago
Contract Strategy Implementation Director at Genentech Managed care contract strategy implementation and rebate/pricing operations leadership for pharma Where South San Francisco, California Level Director, 12+ yrs Pay $209k a year, stated by the employer (middle of the range) Posted Posted 8 days ago ComplianceLegal View the job and apply
Therapeutic Area Analytics & Insights Director - Technical Lead - Cardiovascular, Renal, & Metabolism (CVRM)Director	Genentech	South San Francisco, California	$247k	8+ yrs	8d ago
Therapeutic Area Analytics & Insights Director - Technical Lead - Cardiovascular, Renal, & Metabolism (CVRM) at Genentech Therapeutic area analytics and insights technical lead for cardiovascular, renal and metabolism franchise Where South San Francisco, California Level Director, 8+ yrs Pay $247k a year, stated by the employer (middle of the range) Posted Posted 8 days ago Machine learningSQL View the job and apply
Scientist 3, Microscopy SpecialistSenior	Genentech	South San Francisco, California On-site	$148k	5+ yrs	9d ago
Scientist 3, Microscopy Specialist at Genentech Microscopy specialist supporting drug discovery imaging Where South San Francisco, California (On-site) Level Senior, 5+ yrs Pay $148k a year, stated by the employer (middle of the range) Posted Posted 9 days ago View the job and apply
Therapeutic Area Analytics & Insights Director - Mash Program Lead - Cardiovascular, Renal, & Metabolism (CVRM)Director	Genentech	South San Francisco, California	$247k	–	8d ago
Therapeutic Area Analytics & Insights Director - Mash Program Lead - Cardiovascular, Renal, & Metabolism (CVRM) at Genentech Therapeutic area analytics and insights leadership for a cardiovascular, renal and metabolism commercial portfolio Where South San Francisco, California Level Director Pay $247k a year, stated by the employer (middle of the range) Posted Posted 8 days ago View the job and apply
Senior Product Leader, Therapeutics DiscoverySenior	Genentech	South San Francisco, California	$180k	4–7 yrs	9d ago
Senior Product Leader, Therapeutics Discovery at Genentech Product owner for scientific informatics assay request, setup and data capture products in drug discovery Where South San Francisco, California Level Senior, 4–7 yrs Pay $180k a year, stated by the employer (middle of the range) Posted Posted 9 days ago Machine learningProduct management View the job and apply
Global Head of Platform Technology Development, Autonomous Lab AcceleratorDirector	Genentech	South San Francisco, California On-site	$374k	15+ yrs	11d ago
Global Head of Platform Technology Development, Autonomous Lab Accelerator at Genentech Lead platform technology development for autonomous laboratory systems Where South San Francisco, California (On-site) Level Director, 15+ yrs Pay $374k a year, stated by the employer (middle of the range) Posted Posted 11 days ago Python View the job and apply
Senior Director, Content Studio and Digital OperationsDirector	Genentech	South San Francisco, California	$204k	10+ yrs	12d ago
Senior Director, Content Studio and Digital Operations at Genentech Lead in-house content studio and digital operations for a pharma company Where South San Francisco, California Level Director, 10+ yrs Pay $204k a year, stated by the employer (middle of the range) Posted Posted 12 days ago MarketingSupply chainLegalGenerative AI View the job and apply
User Experience Designer: Hardware SystemsSenior	Zipline	South San Francisco, California	$182k	5+ yrs	12d ago
User Experience Designer: Hardware Systems at Zipline Hardware systems UX design Where South San Francisco, California Level Senior, 5+ yrs Pay $182k a year, stated by the employer (middle of the range) Posted Posted 12 days ago LogisticsUX View the job and apply
Lead Automation Engineer, Autonomous Lab Science & TechnologyLead / Manager	Genentech	South San Francisco, California On-site	$242k	–	12d ago
Lead Automation Engineer, Autonomous Lab Science & Technology at Genentech Technical lead for lab automation platforms: designing robotic work cells, instrumentation and control software for autonomous drug discovery labs Where South San Francisco, California (On-site) Level Lead / Manager Pay $242k a year, stated by the employer (middle of the range) Posted Posted 12 days ago View the job and apply
Global Head, Autonomous Platform Strategy & PortfolioVP / C-level	Genentech	South San Francisco, California	$374k	10+ yrs	12d ago
Global Head, Autonomous Platform Strategy & Portfolio at Genentech Lead strategy and portfolio for autonomous lab platform in pharma R&D Where South San Francisco, California Level VP / C-level, 10+ yrs Pay $374k a year, stated by the employer (middle of the range) Posted Posted 12 days ago View the job and apply
Automation Engineer, Production Equipment	Zipline	South San Francisco, California	$150k	–	13d ago
Automation Engineer, Production Equipment at Zipline Automation engineering for production equipment Where South San Francisco, California Pay $150k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Controls Engineer, Production Equipment	Zipline	South San Francisco, California	$150k	–	13d ago
Controls Engineer, Production Equipment at Zipline Controls engineer for production equipment Where South San Francisco, California Pay $150k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Electrical Engineer, Production Test	Zipline	South San Francisco, California	$135k	–	13d ago
Electrical Engineer, Production Test at Zipline Electrical engineering for production testing Where South San Francisco, California Pay $135k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Industrial Engineer	Zipline	South San Francisco, California	$137k	–	13d ago
Industrial Engineer at Zipline Industrial engineering Where South San Francisco, California Pay $137k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Supply chainLogistics View the job and apply
Lead Manufacturing EngineerLead / Manager	Zipline	South San Francisco, California	$170k	1–3 yrs	13d ago
Lead Manufacturing Engineer at Zipline Lead manufacturing engineering Where South San Francisco, California Level Lead / Manager, 1–3 yrs Pay $170k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Supply chainLogistics View the job and apply
Lead Mechanical Engineer, Production EquipmentLead / Manager	Zipline	South San Francisco, California	$165k	–	13d ago
Lead Mechanical Engineer, Production Equipment at Zipline Production equipment mechanical engineering lead Where South San Francisco, California Level Lead / Manager Pay $165k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Manufacturing Engineer, Early CareerEntry level	Zipline	South San Francisco, California	$117k	–	13d ago
Manufacturing Engineer, Early Career at Zipline Early career manufacturing engineering Where South San Francisco, California Level Entry level Pay $117k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Manufacturing Process EngineerEntry level	Zipline	South San Francisco, California	$137k	1–3 yrs	13d ago
Manufacturing Process Engineer at Zipline Manufacturing process engineering Where South San Francisco, California Level Entry level, 1–3 yrs Pay $137k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Manufacturing Test Engineer	Zipline	South San Francisco, California	$135k	–	13d ago
Manufacturing Test Engineer at Zipline Manufacturing test engineering Where South San Francisco, California Pay $135k a year, stated by the employer (middle of the range) Posted Posted 13 days ago PythonLogistics View the job and apply
Material Flow Engineer	Zipline	South San Francisco, California	$137k	–	13d ago
Material Flow Engineer at Zipline Material flow engineering in manufacturing Where South San Francisco, California Pay $137k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Supply chainLogistics View the job and apply
Mechanical Engineer, Production Equipment	Zipline	South San Francisco, California	$135k	–	13d ago
Mechanical Engineer, Production Equipment at Zipline Mechanical engineering for production equipment Where South San Francisco, California Pay $135k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Supply chainLogistics View the job and apply
Mechanical Engineer, Production Test	Zipline	South San Francisco, California	$135k	–	13d ago
Mechanical Engineer, Production Test at Zipline Mechanical engineering for production test Where South San Francisco, California Pay $135k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Mechatronics Engineer, Production Equipment	Zipline	South San Francisco, California	$132k	–	13d ago
Mechatronics Engineer, Production Equipment at Zipline Mechatronics engineering for production equipment Where South San Francisco, California Pay $132k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Mechatronics Engineer, Production Test	Zipline	South San Francisco, California	$135k	–	13d ago
Mechatronics Engineer, Production Test at Zipline Mechatronics engineering for production test Where South San Francisco, California Pay $135k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Operations Engineer	Zipline	South San Francisco, California	$137k	–	13d ago
Operations Engineer at Zipline Engineering operations Where South San Francisco, California Pay $137k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Supply chainLogistics View the job and apply
Process EngineerEntry level	Zipline	South San Francisco, California	$137k	1–3 yrs	13d ago
Process Engineer at Zipline Process engineering Where South San Francisco, California Level Entry level, 1–3 yrs Pay $137k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Production Equipment & Tooling Engineer	Zipline	South San Francisco, California	$128k	–	13d ago
Production Equipment & Tooling Engineer at Zipline Production equipment and tooling engineering Where South San Francisco, California Pay $128k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Software Engineer, Production Test	Zipline	South San Francisco, California	$135k	–	13d ago
Software Engineer, Production Test at Zipline Production test engineering for devices Where South San Francisco, California Pay $135k a year, stated by the employer (middle of the range) Posted Posted 13 days ago Logistics View the job and apply
Portfolio Leader (Cross Portfolio + S&O)Lead / Manager	Genentech	South San Francisco, California	$240k	10+ yrs	12d ago
Portfolio Leader (Cross Portfolio + S&O) at Genentech Leading cross-portfolio strategy and operations for pharma R&D portfolio management Where South San Francisco, California Level Lead / Manager, 10+ yrs Pay $240k a year, stated by the employer (middle of the range) Posted Posted 12 days ago View the job and apply
Principal Organization Development PartnerLead / Manager	Genentech	South San Francisco, California	$231k	10+ yrs	12d ago
Principal Organization Development Partner at Genentech Organization development and change management consulting for senior leaders Where South San Francisco, California Level Lead / Manager, 10+ yrs Pay $231k a year, stated by the employer (middle of the range) Posted Posted 12 days ago View the job and apply
Senior AI Engineer- ImagingSenior	Genentech	South San Francisco, California Hybrid	$240k	3–5 yrs	2w ago
Senior AI Engineer- Imaging at Genentech Build and deploy computer vision and deep learning models for scientific imaging in biotech Where South San Francisco, California (Hybrid) Level Senior, 3–5 yrs Pay $240k a year, stated by the employer (middle of the range) Posted Posted 14 days ago NoSQLAWSKubernetesMachine learningDeep learningComputer vision View the job and apply

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Questions

How many jobs paying $100k+ are open in South San Francisco, California right now?: 49 listings are open on OpeningsFirst today, all from employers’ own career pages. 0 newer ones went to members by email, within hours of being posted.
Which companies are hiring in South San Francisco, California?: Recent openings here come from Genentech, Goodwin Recruiting, MSD (Merck & Co., Inc.), Zipline, insitro, Exos, Nkarta, Inc., Hearst Communications.
Which site alerts me to new jobs paying $100k+ in South San Francisco, California?: OpeningsFirst emails new jobs paying $100k+ in South San Francisco, California the day employers post them on their own career pages, checking 108,296 career sites. Many never reach LinkedIn. Listings older than 5 days are free to browse here; 49 are open on this page now.
How do I hear about new jobs paying $100k+ in South San Francisco, California first?: Members get new matching jobs by email at 8 am and 6 pm, within hours of being posted, so they apply among the first. It costs $9 a month.

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Other pay levels

Jobs paying $150k+ 30
Jobs paying $200k+ 21