Registered Nurse (RN) jobs in Sumter, South Carolina

41 open Registered Nurse (RN) jobs in Sumter, South Carolina, collected from employers’ own career pages and checked twice a day. Every listing links to the company’s site to apply.

Latest openings

• Registered Nurse (RN)-Acute Care, Rapid Assessment Unit, FT, Nights

  Prisma Health · Sumter
  Posted 2025-08-29
• Registered Nurse (RN)-Acute Care, Intermediate Intensive Care Unit, FT, Nights

  Prisma Health · Sumter
  Posted 2025-10-06
• Registered Nurse (RN)-Home Health, PRN, Days

  Prisma Health · Sumter
  Posted 2025-11-24
• Registered Nurse (RN)-Acute Care, Facility Resource Pool, Tuomey, FT, Nights

  Prisma Health · Sumter
  Posted 2025-12-29
• Registered Nurse (RN)-Acute Care, Facility Resource Pool, Critical Care, FT, Nights

  Prisma Health · Sumter
  Posted 2025-12-29
• Registered Nurse (RN)-Acute Care, Facility Resource Pool, Critical Care, FT, Days

  Prisma Health · Sumter
  Posted 2025-12-29
• Registered Nurse (RN)-Acute Care, Facility Resource Pool, PT, Days

  Prisma Health · Sumter
  Posted 2025-12-29
• Registered Nurse (RN)-Home Health, PT, Days

  Prisma Health · Sumter
  Posted 2026-01-02
• Registered Nurse (RN)-Acute Care, Facility Resource Pool, Critical Care, Part Time, Days

  Prisma Health · Sumter
  Posted 2026-03-17
• Registered Nurse (RN)-Acute Care, Surgical Inpatient, FT, Nights

  Prisma Health · Sumter
  Posted 2026-03-24
• Registered Nurse (RN) Acute Care, Nephrology, FT, Days

  Prisma Health · Sumter
  Posted 2026-05-02
• Registered Nurse (RN) Acute Care, Nephrology, FT, Nights

  Prisma Health · Sumter
  Posted 2026-05-02
• Respiratory Care Shift Coordinator, FT Nights

  Prisma Health · Sumter
  Posted 2026-05-29
• Registered Nurse (RN)-Acute Care, Rapid Assessment Unit, FT, Days

  Prisma Health · Sumter
  Posted 2026-06-02
• Registered Nurse (RN)-Acute Care, Intensive Care Unit, PT, Days

  Prisma Health · Sumter
  Posted 2026-06-10
• Registered Nurse (RN)-Acute Care, Intensive Care Unit, FT, Days

  Prisma Health · Sumter
  Posted 2026-06-10
• Registered Nurse (RN)-Acute Care, Intensive Care Unit, FT, Variable

  Prisma Health · Sumter
  Posted 2026-06-10
• Registered Nurse (RN)-Acute Care, Intermediate Intensive Care Unit, FT, Variable

  Prisma Health · Sumter
  Posted 2026-06-10
• Registered Nurse (RN) - Nurse Resident, December 2026, Intermediate ICU

  Prisma Health · Sumter
  Posted 2026-06-29
• Registered Nurse (RN)-Acute Care, Nephrology, PT, Days

  Prisma Health · Sumter
  Posted 2026-07-03
• Registered Nurse (RN)-Acute Care, Emergency Department, FT, Days

  Prisma Health · Sumter
  Posted 2026-07-10
• Registered Nurse (RN) - Nurse Resident, December 2026, Rapid Assessment

  Prisma Health · Sumter
  Posted 2026-07-11
• Registered Nurse (RN) - Nurse Resident, December 2026, Nephrology

  Prisma Health · Sumter
  Posted 2026-07-11
• Registered Nurse (RN) - Nurse Resident, December 2026, Emergency Department

  Prisma Health · Sumter
  Posted 2026-07-24
• Registered Nurse (RN)-Acute Care, Nephrology, FT, Variable

  Prisma Health · Sumter
  Posted 2026-08-04
• Registered Nurse (RN)-Acute Care, Nephrology, PRN, Days

  Prisma Health · Sumter
  Posted 2026-09-02
• Registered Nurse (RN)-Acute Care, Labor and Delivery, PRN, Variable

  Prisma Health · Sumter
  Posted 2026-09-02
• Registered Nurse (RN)-Acute Care, Emergency Department, FT, Nights

  Prisma Health · Sumter
  Posted 2026-09-09
• Registered Nurse (RN)-Home Health, FT, Days

  Prisma Health · Sumter
  Posted 2026-09-15
• Registered Nurse (RN) - Nurse Resident, Winter 2027, Operating Room

  Prisma Health · Sumter
  Posted 2026-09-18
• Registered Nurse (RN) - Nurse Resident, Winter 2027, Family Birthplace, Labor and Delivery

  Prisma Health · Sumter
  Posted 2026-09-24
• Registered Nurse (RN) - Nurse Resident, Winter 2027, Emergency Department

  Prisma Health · Sumter
  Posted 2026-09-24
• Registered Nurse (RN) - Nurse Resident, Winter 2027, Intermediate ICU

  Prisma Health · Sumter
  Posted 2026-09-28
• Registered Nurse (RN) - Nurse Resident, Winter 2027, ICU

  Prisma Health · Sumter
  Posted 2026-09-28
• Registered Nurse (RN) - Nurse Resident, Winter 2027, Family Beginnings, Nursery

  Prisma Health · Sumter
  Posted 2026-09-30
• Registered Nurse (RN) - Nurse Resident, Winter 2027, General Surgery Inpatient

  Prisma Health · Sumter
  Posted 2026-10-01
• Registered Nurse (RN) - Nurse Resident, Winter 2027, Rapid Assessment

  Prisma Health · Sumter
  Posted 2026-10-01
• Registered Nurse (RN) – Nurse Resident, Winter 2027, Nephrology

  Prisma Health · Sumter
  Posted 2026-10-01
• Registered Nurse (RN) - Nurse Resident, Winter 2027, Oncology

  Prisma Health · Sumter
  Posted 2026-10-01
• RN HSA - Registered Nurse - $7000 Sign on Bonus- Sumter Lee DC

  GENESYS Health Alliance · Sumter
  Posted 2026-10-06
• Registered Nurse RN- Behavioral Health

  Midlands Behavioral Health Hospital · Sumter
  Posted 2024-10-06

Also see

• Entry-level Registered Nurse (RN) jobs in Sumter, South Carolina 13

Registered Nurse (RN) jobs in other cities

• Atlanta, Georgia 759
• Houston, Texas 556
• Dallas, Texas 399
• Los Angeles, California 397
• Miami, Florida 385
• San Antonio, Texas 379
• Jackson, Mississippi 362
• Charlotte, North Carolina 346
• Memphis, Tennessee 344
• Huntsville, Alabama 329
• Cincinnati, Ohio 322
• Chicago, Illinois 322
• Nashville, Tennessee 296
• Grand Rapids, Michigan 284
• New Orleans, Louisiana 273
• Charlottesville, Virginia 265
• Nd, North Dakota 257
• Omaha, Nebraska 256
• Greenville, South Carolina 243
• Augusta, Georgia 243
• Milwaukee, Wisconsin 238
• Jacksonville, Florida 234
• Indianapolis, Indiana 232
• Kansas City, Missouri 223
• Madison, Wisconsin 216

Other roles in Sumter, South Carolina

• Store / Shift Manager 17
• Production / Machine Operator 15
• Physical Therapist 15
• Warehouse Associate / Material Handler 14
• Physician / Doctor 13
• Systems / Network Administrator 12
• Maintenance Technician 12
• Medical Assistant 10

Questions

How many Registered Nurse (RN) jobs are open in Sumter, South Carolina right now?

41 listings are open on OpeningsFirst today, all from employers’ own career pages. 0 more were posted in the last 5 days and went to subscribers first.

Which companies are hiring for Registered Nurse (RN) roles in Sumter, South Carolina?

Recent openings here come from Prisma Health, GENESYS Health Alliance, Midlands Behavioral Health Hospital.

How do I hear about new Registered Nurse (RN) jobs in Sumter, South Carolina first?

Subscribers get new matching jobs by email at 8 am and 6 pm, 5 days before they open on these pages. It costs ₹299 a month.

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